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Taking creatine typically causes a 2-5 pound weight gain in the first week due to water retention in muscles, not fat gain, which is why the scale is a poor indicator of progress

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After 12 weeks (3 months): People on semaglutide lost about 9.6% of their body weight, compared to 2.8% with placebo

Finally, as detailed clinical indications were not consistently available in the national administrative dataset, future research should employ a nested casecontrol design to enable more precise characterization of these variables

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