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In addition, ROS induces both the activation and synthesis of AP-1, a regulator of cell growth, proliferation, and apoptosis [138, 139] and transcription factors such as STAT3, HIF-1, and p53 [118, 140, 141]

Ascorbic Acid, also known as Vitamin C, is a potent antioxidant that can neutralize free radicals in the skin

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500mcg/day)

Despite much excitement in an FcRn receptor-targeted nanoparticle for insulin, 23 there is little sign of widespread activity