Moreover, elevated insulin levels resulting from hyperinsulinemia trigger insulin-like growth factor (IGF) signaling, activating key pathways such as phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) [26]
Metabolic benefits beyond weight loss Weight loss is the headline, but both medications produce metabolic improvements that extend far beyond the number on the scale
Early studies and case reports suggest possible benefits in psoriasis, hidradenitis suppurativa, and wound healing
They also slow the passage of food from the stomach into the small intestine, helping you feel fuller sooner and for longer periods, which can lead to eating less
Filippello A, Di Mauro S, Scamporrino A, Malaguarnera R, Torrisi SA, Leggio GM, et al
The cost: Youll pay a flat $50 monthly copay