glutathione and apoptosis glutathione: beyond an antioxidant Knockdown of microsomal glutathione S-transferase

10.1016/j.addr.2021.04.003 146 SandsE.KivitzA.DehaanW.LeungS

Altered intercellular communication

Mol Cancer Res 16(11):1724-1736, 2018

9 Like vitamin C, uric acid has a principle role in protecting high-oxygen tissues (like the brain) from damage, and low blood uric acid levels have been associated with the progression or increased risk of several neurological disorders, including amyotrophic lateral sclerosis, 10 multiple sclerosis, 11 and Huntington's, 12 Parkinson's, 13 and Alzheimer's diseases

Anyone considering glutathione IV should consult with a qualified physician

The conserved cysteine residue at position 36 in GpoA corresponds to the selenocysteine (Sec) residue at position 46 in human GPX4 (Fig