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Combination pharmacotherapies may achieve greater bodyweight loss than monotherapies, via additive or synergistic effects, when the individual agents target different pathways [12]
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However, combined use requires medical supervision, individualized monitoring of hormone levels, blood counts, and cardiovascular parameters, and careful assessment of each medication's risk-benefit profile
Semaglutide is also being studied in areas such as liver disease (MASH) and Alzheimers, and Novo could achieve a strong share in these nascent markets