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It is hypothesized that CSD, which results in migraine, may be caused by increased neuronal excitability (Sparaco et al., 2006)

The increased expression of tissue factor stimulated by LPS seems to be the result of TLR4 activation, since in TLR4 positive endothelial cells, the production of tissue factor was reduced by treatment with TLR4 antibody [65]

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Among these choices is the question of supplementation, particularly as it pertains to antioxidants like glutathione

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