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212214 GLP-1 RAs reverse detrimental epigenetic changes by promoting the demethylation of the GLP-1R gene, thereby restoring its expression and improving insulin sensitivity

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J Cell Biochem 96(3):653664 Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y et al (2018) Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity

During GLP-1 therapy, rapid metabolic changes and caloric restriction can increase oxidative stress markers in some individuals