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This result suggests that future trials be directed towards patients recently diagnosed with PD to gain the most benefit, since there may be more residual, functional dopamine cells in the SNc that could respond to the growth factor

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This typically resolves quickly and may be related to TB-500's effects on cellular energy metabolism

Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways