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10.1007/s00262-014-1550-y 161 MiyamotoK.WatanabeM.BokuS.SukenoM.MoritaM.KondoH.et al (2020)

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On average, patients may lose between 15% and 20% of their starting weight over 72 weeks when tirzepatide is used in combination with healthy lifestyle changes, such as improved diet and increased physical activity

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However, febuxostat was beneficial in the group of patients without proteinuria and with lower creatinine levels, suggesting that it is more effective in patients with a less renal damage

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