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3 Ferroptosis and neurodegenerative diseases Iron is an essential trace element for maintaining brain function, playing vital roles in neuronal development, neurotransmitter synthesis, mitochondrial energy metabolism, myelin formation, and synaptic plasticity (Table 1), suggesting that therapeutic targeting of ferroptosis may offer a promising strategy for the prevention and treatment of NDDs

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10.1002/14651858.CD005552.pub3 44 GangaleM

Grillo also stars on DirecTVs critically-acclaimed original series Kingdom, which will return for a second season this fall

In this review, the biochemical basis of oxidative stress in ASD is examined, the mechanistic understanding of antioxidant-based interventions is assessed, and the structureactivity relationships that dictate their therapeutic value are discussed

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