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The subcutaneous route has the advantage of a slow release into the bloodstream and is quite convenient for ongoing therapy

In the context of ER stress, the RIDD pathway plays a cytoprotective role, while IRE1 promotes the production of XBP1s, which in turn promotes the expression of genes beneficial to ER stress recovery (Shishova et al., 2022)

Effects of exenatide once weekly plus dapagliflozin, exenatide once weekly alone, or dapagliflozin alone added to metformin monotherapy in subgroups of patients with type 2 diabetes in the DURATION-8 randomized controlled trial

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