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To date, just 13 state Medicaid programs cover GLP-1s to treat obesity, while all states cover the drugs to treat diabetes

If you have a BMI between 35 to 39.9, along with one or more health conditions, or a BMI of 40 or higher, consider consulting with a provider who can explain the advantages of both GLP-1 medications and bariatric surgery

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Statistical analysis Data are presented as means SD

Despite the flexibility within the N-terminal two residues, Glu3 of exendin-4 formed very similar contacts to that of Glu9 of GLP-1, however, interactions with residues residing at the base of the pocket were more transient for exendin-4 (75-80% of the MD frames) than for GLP-1 in the MD simulations (97% of frames for Y152 1 .47 and 100% for R190 2 .60 ) (Supplemental Table 3)

And it's a big one