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When tumors were increased to 100 mm 3 in volume, 100 L of DOX, or DOX/LAAM GSH-CQDs at a dose equivalent to 5 mg kg 1 DOX was injected into the mice veins ( n = 3)

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Curcumin-induced promoter hypermethylation of the mammalian target of rapamycin gene in multiple myeloma cells

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10.1371/journal.pone.0184709 37 KooltheatN.Pankla SranujitR.ChumarkP.PotupP.Laytragoon-LewinN.UsuwanthimK

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This dual-action mechanism may offer a potential advantage in efficacy for some individuals.

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