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BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy

Additional significant biomarkers related to metabolic syndrome include adipokines like adiponectin and leptin

Neurodegenerative disorders Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), Huntingtons disease (HD), and amyotrophic lateral sclerosis (ALS), are characterized by the progressive loss of structure and function of neurons, leading to cognitive and motor impairments [150]

They can enhance (e.g., leptin or resistin) or alleviate (e.g., adiponectin and ghrelin) various features of asthma, acting either pro- or anti-inflammatory, respectively

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