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However, toxicity varies greatly between studies, with the reported incidence of grade 2 gastrointestinal (GI) toxicity ranging from 4 to 30% 22,23,24,25

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2011 Feb 15;589(Pt 4):963-73

"It was really hard for me to take care of my kids just because I wanted to sleep all day long." But she persevered, gradually increasing her dose: "I went up slowly 25, 30, 35, and then 40 for a minute, then hit 50, before starting to go backwards." The key was finding a sustainable routine