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Journal of Haematology, 1992

Thus, the tissue content of GLP-1 is increased in islets from diabetic rodents (106, 110), and when cultured, islets obtained from human donors with T2DM or from diabetic rodents release more GLP-1 ex vivo than non-diabetic islets (98, 109, 113)

These receptors are integral to managing appetite, metabolism, and blood sugar levelscritical factors in weight management

doi: 10.1056/NEJMoa1607141 80 HolmanRRBethelMAMentzRJThompsonVPLokhnyginaYBuseJBet al

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Los pacientes describen evacuaciones menos frecuentes, heces duras o secas, sensacin de evacuacin incompleta y esfuerzo excesivo durante las deposiciones