doi: 10.1016/0735-1097(95)80010-E
The research suggests that approximately 22.4% of people on GLP-1 class medications develop nutritional deficiencies within 12 months, which is one reason regular blood monitoring is recommended throughout treatment
The lipid soluble vitamins, shown in the diagram below, are not as easily eliminated and may accumulate to toxic levels if consumed in large quantity
If that amount creates hardship, the mandatory commitment adds risk
That includes people with moderate to severe obstructive sleep apnea, MASH with moderate to advanced fibrosis, type 2 diabetes, and those using a GLP-1 medication to reduce cardiovascular risk in the setting of established cardiovascular disease
doi:10.1098/rstb.2001.0890