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[DOI] [PubMed] [Google Scholar] 95.Berillo O., Huo K.G., Richer C., Fraulob-Aquino J.C., Briet M., Lipman M.L., Sinnett D., Paradis P., Schiffrin E.L

31,32,33,34,35 For example, the mammalian target of rapamycin (mTOR) signaling pathway is a major mechanism that regulates protein synthesis

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This food effect can effectively double systemic drug exposure without changing the nominal dose an often-overlooked factor in safety discussions

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