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Studies were selected based on their relevance to the interactions between GLP-1 receptor agonists and the gut microbiota, with particular attention to mechanisms potentially influencing treatment response and metabolic outcomes

The problem is systemic, not local

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Literature on endobariatric modalities in MASLD is growing but not explicitly addressed in current societal guidelines [Table 5] [98-102]

At the highest dose, people lost an average of 28% of their body weight when they took retatrutide and stayed on it as prescribed in the trial