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Small amounts of melanin-like granules together with other electron-dense particles can also be seen within large melanosome complexes in the underlying connective tissue
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Less common but more serious side effects can include: Pancreatitis : Inflammation of the pancreas, which can be severe
Guidelines: the 2023 International PCOS Guideline positions GLP-1RAs as practical weight-loss tools for obese women with PCOS but emphasizes that they must be used within a framework of continuous, effective contraception throughout the treatment period, and should not be considered a routine intervention for weight or metabolic management during pregnancy ( Lactation: although preliminary data suggest extremely low milk transfer and no clear adverse signals in infants (163), the overall evidence remains insufficient
McGavran WL 3rd, Sypert GW, Ballinger WE
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