is retatrutide more effective than tirzepatide vs. Tirzepatide: The Next-Gen GLP-1 Showdown How Is Retatrutide Compared to

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Increased heart rate a dose-dependent rise of about 5 to 10 beats per minutewas also seen, peaking around week 24 and declining afterward

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doi: 10.1038/ki.2013.427 84 MimaAHiraoka-YamomotoJLiQKitadaMLiCGeraldesPet al

Tirzepatide has a plasma half-life of approximately 5 days (120 hours), supporting once-weekly subcutaneous dosing