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But let's be absolutely clear from the outset

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This review systematically evaluates the clinical evidence regarding the association between semaglutide use and acid reflux, providing insights into its prevalence, mechanisms, and management strategies

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On the highest dose of 7.2mg, the injection has shown around 21% average weight loss over 72 weeks, while the highest 25mg pill dose has shown up to 22% for early responders over 64 weeks

STEP Trials Overview The STEP 1 trial, one of the most notable studies, reported that a significant majority of participants achieved more than 5% weight loss after 68 weeks on semaglutide