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The physics of oral peptide delivery fundamentally preclude the sustained-release strategies that succeed with small molecules

Leading adenoviral vectors in SARS-CoV-2 clinical trials are adenovirus type 5 vector (Ad5-nCoV) as of 16 March 2020 and chimpanzee adenovirus vaccine vector (ChAdOx1) as of 31 March 2020 by CanSino Biological and the University of Oxford, respectively (Table 1)

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However, GLP-1 receptor agonists like Ozempic may be preferred for individuals with cardiovascular risk factors or those who need additional help managing their blood sugar levels

A one-week titration at 1 mg may improve tolerability before advancing to the full 2 mg dose

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