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Statistical Analyses Data were analyzed using GraphPad prism for windows (version 5, Graphpad Software, San Diego, CA, USA)

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These comparative studies establish the pharmacological basis for the different biological profiles of MT-1 versus MT-II , with MT-1s MC1R preference explaining its predominantly pigmentary and skin photoprotection biology in contrast to MT-IIs broader melanocortin receptor activation producing pro-sexual, pro-erectile, and central appetite effects alongside pigmentation

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They form in your gallbladder, a small organ below your liver that stores bile