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OptumRx, February 2026 prior authorization criteria update Wegovy is FDA-approved for chronic weight management (BMI 30+, or 27+ with a weight-related comorbidity) and for cardiovascular risk reduction in adults with established CVD it is a weight-loss and CV drug, not a diabetes drug

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This decline is not without consequence, leading to a cascade of effects that impact metabolic function and overall well-being: Slowing Metabolism: Lower NAD+ levels can directly translate to reduced metabolic efficiency, making it harder for the body to burn calories and fat effectively

They have evolved from simple diabetes treatments into powerful, multi-faceted therapies that can protect the heart, kidneys, and liver, while also addressing a range of other health concerns

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