SCFAs have previously been implicated in processes such as gastrointestinal function, blood-pressure regulation, circadian rhythm, and immune function, and more recently explored for the effects on BBB physiology [143]
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Specifically, copper's ability to enhance MMP expression, particularly MMP-1, which regulates collagen breakdown, might lead to a temporary increase in cellular debris or a transient inflammatory response as the skin purges and rebuilds
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