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Kaess BM, Pedley A, Massaro JM, Murabito J, Hoffmann U, Fox CS

In such a study (16-week randomized, double-blind, placebo-controlled), 204 individuals with obesity but not diabetes were treated with self-administered subcutaneous injections of pramlintide (nonforced dose escalation 240 g) or placebo three times a day, 15 minutes before meals without concomitant lifestyle intervention (200)

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doi: 10.1016/j.ebiom.2021.103242 94 XiaZDickensMRaingeaudJDavisRJGreenbergME