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Berberine has documented effects on blood sugar regulation

The standard treatment for HFpEF includes sodium-glucose cotransporter 2 inhibitors (SGLT2i), such as empagliflozin and dapagliflozin, supported by the EMPEROR-Preserved (2021) and DELIVER (2022) trials [7, 8]

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Dulaglutide showed benefit, even in broader lower risk diabetes populations