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Due to the continuous exposure to occlusal forces and periodontal microorganisms, alveolar bone possesses a unique immune microenvironment distinct from the long bones, with more frequent interactions between monocytes/macrophages and MSCs (Lin et al., 2021)

Exposure to ultraviolet light will increase the number of melanocytes, resulting in hyperpigmentation and darkening of the skin

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We embrace water as an opportunity, rather than a threat, to engage with this constraint early in the design process, rather than as an afterthought

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