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Chen et al (119) used high levels of GSH reductase in the TME and showed that the disulfide bond (-SS-) in SSBPEI-DOX could be specifically reduced, allowing it to bind to the conventional chemotherapeutic drug DOX and induce apoptosis or necrosis of CSCs

Subsequently, cumulative vasorelaxation concentration-response curves were generated by challenging the pre-contracted rings with increasing concentrations of acetylcholine (10 -9 to 10 -5 M) and then after re-equilibration, to increasing concentrations of sodium nitroprusside (10 -9 to 10 -5 M)

Also, a new higher dose of the injectable version 7.2 mg once weekly may be approved in the near future

Inorganic compounds such as the indium-doped tin oxide (ITO) or MgF 2 were also used to form the pressure-tight coverage and inhibit the thermal decomposition of halide perovskites in a similar manner

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