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Over 68 weeks, patients taking the drug lost 15-20% of their body weight, compared with 2.4% for those taking a placebo in recent clinical trials

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Benefits for Heart, Kidney and Brain Health GLP-1 agonists and SGLT2 inhibitors, both used in managing Type 2 diabetes, show distinct impacts on the heart, kidneys, and brain: Cardiovascular and Renal Effects: SGLT2 inhibitors, such as empagliflozin, significantly reduce the risk of heart failure and cardiovascular mortality in Type 2 diabetes patients

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Since these proteins are markers of cell proliferation, they might be responsible for the acanthotic phenomenon seen in the epithelium of MA [9]