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It really highlights the need for further investigation into their ocular safety profile, first study author Reut Shor, MD, of the Department of Ophthalmology and Vision Sciences at the University of Toronto, Canada, told Healthline

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Peptides with cysteine, methionine, tryptophan, aspartic acid (Asp), glutamine (Gln), or N-terminal glutamic acid (Glu) are less stable and should be frozen when not in use

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It is important to contextualise these results carefully: Phase 2 trials involve relatively small, controlled populations and are not sufficient on their own to establish a medicine's full safety profile or its suitability for broad clinical use