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Ces mdicaments imitent un peptide naturel produit par lorganisme appel GLP-1, une molcule qui joue un rle cl dans la rgulation de lapptit et du mtabolisme, mais qui est dgrade en quelques minutes dans lorganisme par certaines enzymes

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Under normal conditions, NF-B proteins are sequestered in the cytoplasm by inhibitors of B (IBs)

A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R

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Immunogenicity Potential risk of immunogenicity