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Wang 2023 (American Journal of Pathology) Preclinical in vivo, 8 weeks, aged mice, aging-kidney model

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At age 20, plasma levels average around 200 nanograms per milliliter

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There have been rare postmarketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who had residual gastric contents despite reported adherence to preoperative fasting recommendations