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This article reports the landmark trial comparing the effects of semaglutide and tirzepatide at their maximum tolerated doses in adults with obesity, or with overweight and at least one prespecified comorbidity
Stability: Store at -20C and avoid repeated freezing and thawing
It is highly bound to plasma proteins and its elimination half-life is 24 hrs, eliminated in the urine
Safety Considerations: Peptides are usually off-label for injury recovery
// 2~5
Combining mono- and/or dual-agonists to achieve triple agonism may allow for personalisation of treatment, aiming to find the optimal balance of receptor agonism for a specific individual
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