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GLP-1 treatment adds meaningful benefit on top of that but wont replace it

Case reports supporting the data Beyond the retrospective study, multiple case reports have documented TSH suppression after starting GLP-1 agonists in patients on levothyroxine

It is important to note that the frequency of fatigue varies between different GLP-1 products and doses, with higher rates typically seen with the weight management doses compared to the lower doses used for diabetes treatment

Current therapeutic options and limitations The pluripotential roles of IGF-I may explain the interest and wide availability of IGF-I assays from different laboratories

This suggests GLP-1 is the key player for appetite suppression and weight loss, with GIP providing enhancement rather than being equally important

Fatigue or lack of energy: Medications like Vyvanse often help improve energy and motivation