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G6PD deficiency provides some protection against malaria, as do the thalassemias and sickle cell disease also common in these areas, suggesting an evolutionary benefit

The effect depends on dose, delivery method, and consistency

Not appropriate during pregnancy or breastfeeding Epithalon is not used during pregnancy or breastfeeding

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When high doses of vitamin B 12 are given orally, only a small percentage can be absorbed, which may explain the low toxicity (4)

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