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18, 23 Moreover, cells derived from solid tumors that undergo loss of attachment (LOA) to the extracellular matrix (known as anoikis) display inhibition of glucose uptake and catabolism, which results in the loss of ATP, NADPH (as a result of decreased flux through the pentose phosphate pathway) and increased production of reactive oxygen species (ROS)

Luo et al., 2022

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