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Lever presses during the 30-s ITI were neither rewarded with food pellets nor punished with extra time-out

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Severe caloric restriction below 1,000 to 1,200 calories daily triggers an aggressive metabolic conservation response that can halt weight loss even in the presence of a large theoretical calorie deficit

For embryonic lethality, the number of unhatched eggs after 24 h was recorded (re-checked after 48 h)