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In PD, GLP-1RAs prevented the progression of loss of nigrostriatal dopaminergic cells, restored dopamine synthesis, showed anti-inflammatory activity, and improved motor functions [45]

Figure 1: Changes in gross morphological scores amongst the four experimental treatment groups

Unlike some other causes of dark spots, medication-related pigmentation might persist as long as the medication is continued

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The brain, pancreas, lung, and kidney of wild-type C57BL/6JNifdc mice (+/+) showed mouse GLP1R positive (A-D)

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