GLP-1 works on multiple fronts: it enhances insulin secretion, inhibits glucagon production (reducing blood sugar), and delays gastric emptying, which leads to increased feelings of fullness (satiety)
The key decision for this weight range is whether to target 8 mg or push to 12 mg
Stubborn fat deposits that resisted previous diet and exercise efforts may begin responding
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Why some muscle loss happens during any significant weight loss Before blaming retatrutide specifically, understand that muscle loss during weight loss is a biological reality, not a medication side effect
Follow-up Repeat broad labs after 8-12 weeks if systemic use continues or symptoms change