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Serious bacterial infections requiring hospitalization or intravenous antibiotics may occur and appear to be more prevalent during the first 6 to 12 months of TNF inhibitor therapy, likely because patients at greatest risk may develop this complication early, then discontinue therapy

Oral malignant melanoma, a rare neoplasm of melanocytes, accounts for less than 1% of melanomas and 0.5% of oral malignancies

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This is more personalized than the traditional approach of recommending a treatment to a large group of people based on broad factors