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Understanding the Science The science of GHK-Cu is grounded in three interconnected areas: copper biochemistry in mammalian tissues, the coordination chemistry of histidine-containing peptides, and the cellular and tissue-level biology in which the tripeptide and the copper it carries have been studied

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In this sense, proline metabolism in cancer-associated fibroblasts (CAFs) is critical for the synthesis of ECM that supports tumor growth and metastasis [98]

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