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For patients with type 2 diabetes, GLP-1 medications are generally considered long-term therapy as part of individualized disease management

BPC is a naturally occurring protein in the digestive tract

Author Contributions Jos Luis Grriz provided expert clinical opinion and critical revision of the manuscript for important intellectual content and has helped establish the structure and contents of the manuscript

Retatrutide is a triple GLP-1/GIP/glucagon receptor agonist under clinical investigation

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Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer