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10.1038/s41580-020-00324-8 71 JiangZ.-B.WangW.-J.XuC.XieY.-J.WangX.-R.ZhangY.-Z.et al (2021b)

And IGF-1 isn't in the first one

Moreover, lipid peroxidation-driven plasma membrane rupture will accelerate KRAS-mediated pancreatic tumorigenesis by promoting DAMPs release, resulting in the activation of inflammatory pathways and polarization of macrophages for tumor growth [234]

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Furthermore, it decreased the expression of key mesenchymal markers like N-cadherin and vimentin, indicating that STC2 plays a role in promoting the EMT phenotype