The effect of competition for binding to this site was appreciated for the first time in 1970, when Morell and colleagues showed that the plasma half-life of IgG is inversely related to the concentration of IgG [93]
So really, everyone is just doing their best guess and playing it safe by saying to avoid these ingredients
Interestingly, higher concentrations such as 1 mM and 2 mM did not yield similar protective effects, indicating a dose-dependent response and identifying 0.1 mM as the optimal concentration for reactive oxygen species mitigation [2]
The chemistry concern is that disrupting the chelate releases free copper, which behaves very differently in formulation than the chelated peptide
Testagen 20mg Summary Description: Testagen is a synthetic, short peptide bioregulator that targets the regulation and restoration of testicular and endocrine system functions
Clinical Research Findings In a controlled study using a collagenase-induced osteoarthritis rabbit model, researchers administered weekly intra-articular injections of 0.25 mg AOD-9604 for 4-7 weeks
