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The GDS-15 was completed by 34 patients (17 per group), with median scores initially at 2.0 in the loading dose group and 3.5 in the no loading dose group, which adjusted to 2.5 and 2.0 respectively after 90 days
A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men
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Topical anti-aging effects are biologically plausible because collagen, glycosaminoglycans, skin elasticity, fibroblasts, and extracellular matrix remodeling are all directly relevant to skin aging [2], [4], [12]
