The Explosion of GLP-1 Popularity: From 2021 Onward Following Wegovy's approval in 2021, GLP-1 medications transitioned from specialty pharmaceuticals to household names within three years
Interestingly, adult mice with modest isolated elevations in GH and IGF-1 levels have greater lean mass, improved lipid oxidation and glucose clearance 38 , while specific, temporal reductions in GH and IGF-1 in adults have been linked to deleterious metabolic effects, including impaired hepatic insulin action 38 , and reduced -cell mass and function 39
MASH Therapy in 2026: Semaglutide vs Resmetirom Semaglutide leads in MASH resolution, weight loss, and metabolic improvement, while Resmetirom offers a targeted liver approach with strong fibrosis and lipid benefits
Gomes MJ, Martinez PF, Pagan LU, et al
Perforation occurs in 1 : 1000 examinations but this is higher (up to 2%) after polypectomy (see Practical Box 6.2)
Those three together protein, fiber, water are the nutrition basics that often need extra attention during a GLP-1 routine
