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Laboratory studies demonstrate that senescent cancer cells maintain similar FOXO4-p53 interactions that protect them from apoptosis, making them susceptible to FOXO4-DRI-mediated elimination while providing researchers with tools for studying cancer cell senescence and survival mechanisms
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Abbreviations: MASH, metabolic dysfunction-associated steatohepatitis
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10.1016/s0021-9258(17)41960-0 132 VanoniM
It also plays a vital role in the detoxification process, helping the liver neutralise and eliminate metabolic waste and environmental toxins
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