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Pathway enrichment analysis of these differentially prevalent metabolites revealed significant perturbations in metabolic networks including branched-chain aminoacids degradation, glutathione metabolism, threonine and 2-oxobutanoate degradation, gluconeogenesis, pyruvate metabolism, and glycine and serine metabolism (Figure S5)

Evaluation of the relationship between GPR43 and adiposity in human

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32 Results also showed improvement in the metabolic risk factors such as weight, glucose and high-density lipoprotein cholesterol levels